People with the given name

• Natsume (drummer) ( 夏芽 ), a Japanese drummer and voice actress
• Natsume Akatsuki ( 暁 なつめ ), a Japanese writer of light novels and manga
• Natsume Mito ( 三戸 なつめ ; born 1990), a Japanese model, singer, and presenter
• Natsume Ono ( オノ ナツメ ; born 1977), a Japanese manga artist
• Natsume Sano ( 佐野 夏芽 ; born 1985), a Japanese gravure idol

People with the surname

• Fusanosuke Natsume (夏目 房之介), born in 1950, is a Japanese writer and cartoonist.
• Masako Natsume (夏目 雅子), born in 1957 and died in 1985, was a Japanese actor.
• Nana Natsume (夏目 ナナ), born in 1980, was a former Japanese adult video (AV) actress.
• Rio Natsume (夏目 理緒), born in 1985, is a Japanese gravure idol.
• Shingo Natsume (夏目 真悟), born in 1980, is a Japanese director.
• Suzu Natsume (夏目 鈴), born in 1991, is a Japanese actress.
• Sōseki Natsume (夏目 漱石), born in 1867 and died in 1916, was a Japanese novelist from the early 1900s.
• Yoshinobu Natsume (夏目 吉信), born in 1517 and died in 1573, was a Japanese samurai.
• Yoshinori Natsume (夏目 義徳), born in 1975, is a Japanese manga artist.
• Yuki Natsume (棗 佑喜), born in 1988, is a Japanese footballer.

Fictional characters

• Atsuko Natsume is the main character in the anime and manga series All Purpose Cultural Cat Girl Nuku Nuku.
• Natsume is a character from the Pokémon series, called Sabrina in the English version.
• Natsume Hyūga is a character in the anime and manga series Alice Academy.
• Natsume Takashi is the main character in the manga and anime series Natsume's Book of Friends.
• Maya Natsume is a character in the anime series Tenjho Tenge.
• Asako Natsume is a character in the manga series My Little Monster (Tonari No Kaibutsu-kun).
• Mio Natsume is a character in the tokusatsu series Ressha Sentai ToQger.
• Mio Natsume is also a character in the anime series Just Because!.
• Natsume, known as "Coco" in English, is a character in the anime series Fighting Foodons.
• Mai Natsume is a character from the video game series BlazBlue.
• Natsume is a character in the anime series Deca-Dence.
• Natsume is a character in the anime series Hidamari Sketch.
• Sakasaki Natsume is a character in the idol rhythm game Ensemble Stars!.

Companies

• Natsume Atari, which was once called Natsume Co., Ltd., is a Japanese company that makes and sells video games. It was started in 1987.
• Natsume Inc. is an American company that sells video games. It was started in 1988 as part of the Japanese company but became its own separate company later.

Other uses

• Natsume (ナツメ) / 棗 is the Japanese name for a fruit called jujube, which is also known as Ziziphus jujuba.
• Natsume (棗; "jujube") refers to a type of chaki, which is a small container used to hold tea leaves during the Japanese tea ceremony.
• Natsume (なつめ) was the former name of Sanjuro, who was the Lord of Bitchū Matsuyama Castle.